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TRA2B Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Transformer 2 beta homolog

Gene Aliases

Htra2-beta; PPP1R156; protein phosphatase 1, regulatory subunit 156; SFRS10; Splicing factor, arginine/serine-rich 10; splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) ; SRFS10; TRA-2 beta; TRA2-BETA; TRAN2B; transformer-2 protein homolog B; transformer-2 protein homolog beta.

Gene ID

6434

Accession Number

NP_001230808.1

Reactivity

Homo sapiens|Human

Target

Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA.

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

19kDa

Protein Length

Recombinant

NCBI Gene Symbol

TRA2B

Host or Source

E.coli

Protein Name

Transformer-2 protein homolog beta

Gene Name URL

TRA2B

Nucleotide Accession Number

NM_001243879.1

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