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SYTL2 Recombinant Protein

Selected Variant

OPCD07264-50UG

Size: 50 µg

Product Specifications

CAS Number

9000-83-3

Gene Name

Synaptotagmin like 2

Gene Aliases

Breast cancer-associated antigen SGA-72M; CHR11SYT; chromosome 11 synaptotagmin; EXO4; exophilin-4; PPP1R151; protein phosphatase 1, regulatory subunit 151; SGA72M; SLP2; SLP2A; synaptotagmin-like protein 2.

Gene ID

54843

Accession Number

NP_001156423.1

Reactivity

Homo sapiens|Human

Target

Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol-4,5-bisphosphate (PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca (2+) while binding to PIP2 is Ca (2+) insensitive.

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

33kDa

Protein Length

Recombinant

NCBI Gene Symbol

SYTL2

Host or Source

E.coli

Protein Name

Synaptotagmin-like protein 2

Gene Name URL

SYTL2

Nucleotide Accession Number

NM_001162951.2

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