SLPI Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Secretory leukocyte peptidase inhibitor
Gene Aliases
ALP; antileukoproteinase; secretory leukocyte protease inhibitor.
Gene ID
20568
Accession Number
NP_035544.1
Reactivity
Mouse|Mus musculus
Target
Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G (PubMed:9126337) . Modulates the innate immune response after bacterial infection (PubMed:12615907) . Contributes to regulate the inflammatory and immune responses to the intracellular parasite L.major (PubMed:25030421) . Down-regulates responses to bacterial lipopolysaccharide (LPS) (PubMed:9039268, PubMed:12615907, PubMed:25030421) . Plays a role in regulating the activation of NF-kappa-B and inflammatory responses (PubMed:11017147, PubMed:12615907) . Has antimicrobial activity against mycobacteria, but not against salmonella (PubMed:18322212) . Contributes to normal resistance against infection by M.tuberculosis (PubMed:18322212) . Required for normal resistance to L.major (PubMed:25030421) . Required for normal wound healing, probably by preventing tissue damage by limiting protease activity (PubMed:11017147, PubMed:25030421) . Together with ELANE, required for normal differentiation and proliferation of bone marrow myeloid cells (By similarity) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
500 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
20kDa
Protein Length
Recombinant
NCBI Gene Symbol
Slpi
Host or Source
E.coli
Protein Name
Antileukoproteinase
Gene Name URL
Slpi
Nucleotide Accession Number
NM_011414.3
Frequently Asked Questions
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