What is the catalog number for SIRT3 Recombinant Protein?

The catalog number for SIRT3 Recombinant Protein is OPCD07003-200UG.

What sizes are available for SIRT3 Recombinant Protein?

SIRT3 Recombinant Protein is available in the following size(s): 200 µg.

Is SIRT3 Recombinant Protein in stock?

SIRT3 Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

SIRT3 Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Sirtuin 3

Gene Aliases

2310003L23Rik; AI848213; mitochondrial protein lysine deacetylase; mSIR2L3; NAD-dependent deacetylase sirtuin-3; NAD-dependent protein deacetylase sirtuin-3; regulatory protein SIR2 homolog 3; Si; silent mating type information regulation 2, (S.cerevisiae, homolog) -like 3; Sir2l3; SIR2-like protein 3; SIRT3L mitochondrial.

Gene ID

64384

Accession Number

NP_001120823.1

Reactivity

Mouse|Mus musculus

Target

NAD-dependent protein deacetylase (PubMed:23835326, PubMed:17923681, PubMed:18794531, PubMed:21172655) . Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues (PubMed:23835326, PubMed:17923681, PubMed:18794531, PubMed:21172655) . Known targets include ACSS1, IDH, GDH, PDHA1, SOD2, LCAD, SDHA and the ATP synthase subunit ATP5O (PubMed:16790548, PubMed:18794531, PubMed:21172655) . Contributes to the regulation of the cellular energy metabolism (PubMed:23835326) . Important for regulating tissue-specific ATP levels (PubMed:18794531, PubMed:24252090) . In response to metabolic stress, deacetylates transcription factor FOXO3 and recruits FOXO3 and mitochondrial RNA polymerase POLRMT to mtDNA to promote mtDNA transcription (PubMed:23283301) .

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

29/16kDa

Protein Length

Recombinant

NCBI Gene Symbol

Sirt3

Host or Source

E.coli

Protein Name

NAD-dependent protein deacetylase sirtuin-3

Gene Name URL

Sirt3

Nucleotide Accession Number

NM_001127351.1

Frequently Asked Questions

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