SIGLEC7 Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Sialic acid binding Ig like lectin 7
Gene Aliases
Adhesion inhibitory receptor molecule 1; adhesion inhibitory receptor molecule 1, siglec-7; AIRM1; AIRM-1; CD328; CDw328; D-siglec; p75; p75/AIRM1; QA79; QA79 membrane protein; sialic acid binding immunoglobulin-like lectin 7; sialic acid-binding Ig-like lectin 7; SIGLEC19P; SIGLEC-7; SIGLECP2.
Gene ID
27036
Accession Number
NP_001264130.1
Reactivity
Homo sapiens|Human
Target
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide) . The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
18kDa
Protein Length
Recombinant
NCBI Gene Symbol
SIGLEC7
Host or Source
E.coli
Protein Name
Sialic acid-binding Ig-like lectin 7
Gene Name URL
SIGLEC7
Nucleotide Accession Number
NM_001277201.1
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV689767 1.0 µg DNA
Prl7a3 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details bs-20003R-APC-Cy5.5 100 µL
RUNX2 Polyclonal Antibody, APC-Cy5.5 Conjugated
Sign In for Pricing
View Details 
129687 50 µg
MIDN (Midnolin, Midbrain Nucleolar Protein, DKFZp547M072)
Sign In for Pricing
View Details E53A07080 50 µg
Recombinant Mouse GPA33 / Glycoprotein A33 Protein (His tag)
Sign In for Pricing
View Details E44H11638 100 µL
GAPDH Monoclonal Antibody (2B8), AbFluor™ 555 Conjugated
Sign In for Pricing
View Details