SIGLEC12 Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Sialic acid binding Ig-like lectin E
Gene Aliases
Cd170; MIS; mSigle; mSiglec-E; myeloid inhibitory siglec; sialic acid binding Ig-like lectin 5; sialic acid-binding Ig-like lectin 12; Sialic acid-binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin E; sialic acid-binding Ig-like lectin-like 1; sialic acid-binding immunoglobulin-like lectin E; Sigl; siglec-12; Siglec12; siglec-5; Siglec5; Siglec9; siglec-E; siglec-L1; Siglecl1; SIGLEC-like 1.
Gene ID
83382
Accession Number
NP_112458.2
Reactivity
Mouse|Mus musculus
Target
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules.
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
25kDa
Protein Length
Recombinant
NCBI Gene Symbol
Siglece
Host or Source
E.coli
Protein Name
Sialic acid-binding Ig-like lectin 12
Gene Name URL
Siglece
Nucleotide Accession Number
NM_031181.2
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