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RNASE7 Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Ribonuclease A family member 7

Gene Aliases

RAE1; ribonuclease 7; ribonuclease, RNase A family, 7; RNase 7; SAP-2; skin-derived antimicrobial protein 2.

Gene ID

84659

Accession Number

NP_115961.2

Reactivity

Homo sapiens|Human

Target

Exhibits a potent RNase activity (PubMed:12244054, PubMed:12527768, PubMed:17150966) . Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium (PubMed:12244054, PubMed:12527768, PubMed:25075772, PubMed:17150966) . Causes loss of bacterial membrane integrity (PubMed:17150966) . Probably contributes to urinary tract sterility (PubMed:25075772) . Bactericidal activity is independent of RNase activity (PubMed:17150966) .

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

18kDa

Protein Length

Recombinant

NCBI Gene Symbol

RNASE7

Host or Source

E.coli

Protein Name

Ribonuclease 7

Gene Name URL

RNASE7

Nucleotide Accession Number

NM_032572.3

Frequently Asked Questions

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