RFTN1 Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Raftlin, lipid raft linker 1
Gene Aliases
Cell migration-inducing gene 2 protein; MIG2; PIB10; PIG9; proliferation-inducing protein 10; proliferation-inducing protein 9; raftlin; raft-linking protein.
Gene ID
23180
Accession Number
NP_055965.1
Reactivity
Homo sapiens|Human
Target
Involved in protein trafficking via association with clathrin and AP2 complex (PubMed:27022195, PubMed:21266579) . Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages; and internalization of poly (I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells; resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed:27022195, PubMed:21266579) . Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (By similarity) . May regulate B-cell antigen receptor-mediated signaling (PubMed:12805216) . May play a pivotal role in the formation and/or maintenance of lipid rafts (PubMed:12805216) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
38kDa
Protein Length
Recombinant
NCBI Gene Symbol
RFTN1
Host or Source
E.coli
Protein Name
Raftlin
Gene Name URL
RFTN1
Nucleotide Accession Number
NM_015150.1
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