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RFTN1 Recombinant Protein

Selected Variant

OPCD06579-10UG

Size: 10 µg

Product Specifications

CAS Number

9000-83-3

Gene Name

Raftlin, lipid raft linker 1

Gene Aliases

Cell migration-inducing gene 2 protein; MIG2; PIB10; PIG9; proliferation-inducing protein 10; proliferation-inducing protein 9; raftlin; raft-linking protein.

Gene ID

23180

Accession Number

NP_055965.1

Reactivity

Homo sapiens|Human

Target

Involved in protein trafficking via association with clathrin and AP2 complex (PubMed:27022195, PubMed:21266579) . Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages; and internalization of poly (I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells; resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed:27022195, PubMed:21266579) . Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (By similarity) . May regulate B-cell antigen receptor-mediated signaling (PubMed:12805216) . May play a pivotal role in the formation and/or maintenance of lipid rafts (PubMed:12805216) .

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

38kDa

Protein Length

Recombinant

NCBI Gene Symbol

RFTN1

Host or Source

E.coli

Protein Name

Raftlin

Gene Name URL

RFTN1

Nucleotide Accession Number

NM_015150.1

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