PTN Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Pleiotrophin
Gene Aliases
HARP; HBBM; HB-GAM; HBGF8; HBGF-8; HBNF; HBNF-1; heparin affin regulatory protein; heparin-binding brain mitogen; heparin-binding growth factor 8; heparin-binding growth-associated molecule; heparin-binding neurite outgrowth promoting factor; heparin-binding neurite outgrowth-promoting factor 1; NEGF1; OSF-1; osteoblast-specific factor 1; pleiotrophin; pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1) .
Gene ID
5764
Accession Number
NP_001308315.1
Reactivity
Homo sapiens|Human
Target
Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells (PubMed:1768439, PubMed:1733956) . Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation (PubMed:11278720) . Binds to cell-surface target proteins via their chondroitin sulfate groups (PubMed:26896299) . Down-regulates PTPRZ1 activity (PubMed:16814777) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
18kDa
Protein Length
Recombinant
NCBI Gene Symbol
PTN
Host or Source
E.coli
Protein Name
Pleiotrophin
Gene Name URL
PTN
Nucleotide Accession Number
NM_001321386.1
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