PTHLH Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Aliases
Parathyroid hormone-like protein.
Reactivity
Mouse|Mus musculus
Target
Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath.
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
50 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
18/19kDa
Protein Length
Recombinant
NCBI Gene Symbol
PTHLH
Host or Source
E.coli
Protein Name
Parathyroid hormone-related protein
Gene Name URL
PTHLH
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6377686-01 0.1 mL
ESD (S-formylglutathione Hydrolase, FGH, Esterase D) (MaxLight 550)
Ask
View Details 
MBS6377686-02 5x 0.1 mL
ESD (S-formylglutathione Hydrolase, FGH, Esterase D) (MaxLight 550)
Ask
View Details MBS1108316-01 0.5 mg (E-Coli)
Recombinant Mouse Oncostatin-M-specific receptor subunit beta (Osmr), partial
Ask
View Details MBS1108316-02 0.05 mg (Baculovirus)
Recombinant Mouse Oncostatin-M-specific receptor subunit beta (Osmr), partial
Ask
View Details 
MBS1108316-03 0.5 mg (Yeast)
Recombinant Mouse Oncostatin-M-specific receptor subunit beta (Osmr), partial
Ask
View Details