EMD638683 (R-Form)
EMD638683 R-Form is the R-form of EMD638683. EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM.
Product Specifications
CAS Number
[1184940-47-3]
UNSPSC
12352005
Target
SGK
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/EMD638683-R-Form.html
Purity
99.86
Solubility
DMSO : 66.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1=C(CC)C(C(NNC([C@H](O)C2=CC(F)=CC(F)=C2)=O)=O)=CC=C1O
Molecular Formula
C18H18F2N2O4
Molecular Weight
364.34
References & Citations
[1]Ackermann TF, et al. EMD638683, a novel SGK inhibitor with antihypertensive potency. Cell Physiol Biochem. 2011;28 (1) :137-46.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SGK1
Available Sizes
Curated Selection
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