PRDM1 Recombinant Protein
Product Specifications
Gene Name
PR domain containing 1, with ZNF domain
Gene Aliases
B lymphocyte induced maturation protein; B lymphocyte-induced maturation protein 1; b2b1765C; b2b1765Clo; beta-interferon gene positive regulatory domain I-binding factor; Bli; Blim; Blimp1; Blimp-1; PR domain zinc finger protein 1; PR domain-containing protein 1; PRDI-; PRDI-BF1; ZNFPR1A1.
Gene ID
12142
Accession Number
NP_031574.2
Reactivity
Mouse|Mus musculus
Target
Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs (PubMed:27102484) . Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection (PubMed:27102484) . Binds specifically to the PRDI element in the promoter of the beta-interferon gene (By similarity) . Drives the maturation of B-lymphocytes into Ig secreting cells (By similarity) . Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions (PubMed:27102484) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
34kDa
Protein Length
Recombinant
NCBI Gene Symbol
Prdm1
Host or Source
E.coli
Protein Name
PR domain zinc finger protein 1
Gene Name URL
Prdm1
CAS Number
9000-83-3
Nucleotide Accession Number
NM_007548.4
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