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NUP50 Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Nucleoporin 50

Gene Aliases

1700030K07Rik;50 kDa nucleoporin; AI413123; Np; Npap60; nuclear pore associated protein 60 kDa; nuclear pore complex protein Nup50; Nuclear pore-associated protein 60 kDa-like; nucleoporin Nup50; nucleoprotein 50.

Gene ID

18141

Accession Number

NP_057923.2

Reactivity

Mouse|Mus musculus

Target

Component of the nuclear pore complex that has a direct role in nuclear protein import (PubMed:10811608) . Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling (PubMed:16222336) . Interacts with regulatory proteins of cell cycle progression including CDKN1B (PubMed:10891500, PubMed:10811608) . This interaction is required for correct intracellular transport and degradation of CDKN1B (PubMed:10811608) .

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

34kDa

Protein Length

Recombinant

NCBI Gene Symbol

Nup50

Host or Source

E.coli

Protein Name

Nuclear pore complex protein Nup50

Gene Name URL

Nup50

Nucleotide Accession Number

NM_016714.2

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