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NOS2 Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Nitric oxide synthase 2, inducible

Gene Aliases

Inducible nitric oxide synthase; inducible NO synthase; inducible NOS; iNOS; i-NOS; MAC-NOS; macrophage NOS; N; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase, inducible; No; NOS type II; Nos-2; Nos2a; NOS-II; peptidyl-cysteine S-nitrosylase NOS2.

Gene ID

18126

Accession Number

NP_001300850.1

Reactivity

Mouse|Mus musculus

Target

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7503239) . In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (PubMed:16373578) . As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (By similarity) . Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8 (By similarity) .

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

20kDa

Protein Length

Recombinant

NCBI Gene Symbol

Nos2

Host or Source

E.coli

Protein Name

Nitric oxide synthase, inducible

Gene Name URL

Nos2

Nucleotide Accession Number

NM_001313921.1

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