MMP14 Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Matrix metallopeptidase 14 (membrane-inserted)
Gene Aliases
AI325305; matrix metalloproteinase 14 (membrane-inserted) ; matrix metalloproteinase-14; Membrane type 1-MMP; Membrane-type matrix metalloproteinase 1; membrane-type-1 matrix metalloproteinase; MMP-X1; MT1-MM; MT1-MMP; MT-MMP; MT-MMP-1; sa; sabe; type 1 matrix metalloprotease 14.
Gene ID
17387
Accession Number
NP_032634.3
Reactivity
Mouse|Mus musculus
Target
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development (PubMed:10520996) . May be involved in actin cytoskeleton reorganization by cleaving PTK7 (By similarity) . Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues (By similarity) . Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis (By similarity) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
44kDa
Protein Length
Recombinant
NCBI Gene Symbol
Mmp14
Protein Name
Matrix metalloproteinase-14
Gene Name URL
Mmp14
Nucleotide Accession Number
NM_008608.4
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