CCL4 Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
C-C motif chemokine ligand 4|C-C motif chemokine ligand 4 like 1
Gene Aliases
ACT2; AT744.1; AT744.2; CC chemokine ligand 4L1; C-C motif chemokine 4; C-C motif chemokine 4-like; CCL4L; chemokine (C-C motif) ligand 4; chemokine (C-C motif) ligand 4-like 1, telomeric; G-26; G-26 T-lymphocyte-secreted protein; HC21; LAG1; LAG-1; lymphocyte activation gene 1 protein; macrophage inflammatory protein 1-beta; macrophage inflammatory protein-1b2; MIP1B; MIP1B1; MIP-1-beta; MIP-1-beta (1-69) ; Monocyte adherence-induced protein 5-alpha; PAT 744; Protein H400; SCYA2; SCYA4; SCYA4L; SCYA4L1; SCYA4L2; secreted protein G-26; SIS-gamma; small inducible cytokine A4 (homologous to mouse Mip-1b) ; small inducible cytokine A4-like; Small-inducible cytokine A4; Small-inducible cytokine A4-like; T-cell activation protein 2.
Gene ID
388372|6351
Accession Number
NP_002975.1
Reactivity
Homo sapiens|Human
Target
Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV) . The processed form MIP-1-beta (3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta (3-69) is also a ligand for CCR1 and CCR2 isoform B.
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
40kDa
Protein Length
Recombinant
NCBI Gene Symbol
CCL4|CCL4L1
Host or Source
E.coli
Protein Name
C-C motif chemokine 4
Gene Name URL
CCL4|CCL4L1
Nucleotide Accession Number
NM_002984.3
Curated Selection
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