What is the catalog number for ITGAV Recombinant Protein?

The catalog number for ITGAV Recombinant Protein is OPCD04585-10UG.

What sizes are available for ITGAV Recombinant Protein?

ITGAV Recombinant Protein is available in the following size(s): 10 µg.

Is ITGAV Recombinant Protein in stock?

ITGAV Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

ITGAV Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Integrin alpha V

Gene Aliases

1110004F14Rik;2610028E01Rik; alpha v integrin; CD51; D430040G12Rik; integrin alpha-V; vitronectin receptor alpha polypeptide (VNRA) ; vitronectin receptor subunit alpha.

Gene ID

16410

Accession Number

NP_032428.2

Reactivity

Mouse|Mus musculus

Target

The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing (PubMed:9827803) . ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling. ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV:ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling (By similarity) . ITGAV:ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling (By similarity) . ITGAV:ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling (By similarity) . ITGAV:ITGB3 binds to IL1B and this binding is essential for IL1B signaling (By similarity) . ITGAV:ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (By similarity) . ITGAV:ITGB3 and ITGAV:ITGB6 act as a receptor for fibrillin-1 (FBN1) and mediate R-G-D-dependent cell adhesion to FBN1.

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol