IFNAR2 Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Interferon alpha and beta receptor subunit 2

Gene Aliases

Human interferon alpha/beta receptor; IFNABR; IFN-alpha/beta receptor 2; IFNalpha/beta receptor subunit 2; IFN-alpha-REC; IFNARB; IFN-R; IFN-R-2; IMD45; interferon (alpha, beta and omega) receptor 2; interferon alpha binding protein; interferon alpha/beta receptor 2; interferon receptor; interferon-alpha/beta receptor beta chain; type I interferon receptor 2.

Gene ID

3455

Accession Number

NP_000865.2

Reactivity

Homo sapiens|Human

Target

Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation (PubMed:26424569) . Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1 (PubMed:8181059, PubMed:7665574, PubMed:7759950) . Isoform 3 is a potent inhibitor of type I IFN receptor activity (PubMed:7759950) .

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol