ICK Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Ciliogenesis associated kinase 1

Gene Aliases

Heart serine-threonine protein kinase; Ick; intestinal cell (MAK-like) kinase; intestinal cell kinase; MAK-related kinase; MRK; serine/threonine-protein kinase ICK.

Gene ID

84411

Accession Number

NP_620241.1

Reactivity

Rat|Rattus norvegicus

Target

Required for ciliogenesis, particularly in neuronal and retinal progenitor cells (By similarity) . Phosphorylates KIF3A (By similarity) . Involved in the control of ciliary length (By similarity) . Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity) . May play a role in cardiac development (PubMed:8570168) . Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity (By similarity) .

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol