HSD17B12 Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Hydroxysteroid (17-beta) dehydrogenase 12
Gene Aliases
17-beta-HSD 12;17-beta-hydroxysteroid dehydrogenase 12;2610510O05Rik;3-ketoacyl-CoA reductase; AI172963; estradiol 17-beta-dehydrogenase 12; KAR; keratoadhesin; keratonectin; KIK; Kik1; KIK-I; steroid dehydrogenase; very-long-chain 3-oxoacyl-CoA reductase.
Gene ID
56348
Accession Number
NP_062631.1
Reactivity
Mouse|Mus musculus
Target
Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation.
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
80 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
64kDa
Protein Length
Recombinant
NCBI Gene Symbol
Hsd17b12
Host or Source
E.coli
Protein Name
Very-long-chain 3-oxoacyl-CoA reductase
Gene Name URL
Hsd17b12
Nucleotide Accession Number
NM_019657.4
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
