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FKBP8 Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

FK506 binding protein 8

Gene Aliases

38 kDa FK506-binding protein;38 kDa FKBP;38kD;38kDa; FK506-binding protein 38; FK506-binding protein 8; Fkbp3; Fkbp38; FKBP-38; FKBP-8; FKBPR38; mFKBP38; peptidyl-prolyl cis-trans isomerase FKBP8; PPIase FKBP8; rotamase.

Gene ID

14232

Accession Number

NP_001104536.1

Reactivity

Mouse|Mus musculus

Target

Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis (By similarity) . Required for normal embryonic development.

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

26kDa

Protein Length

Recombinant

NCBI Gene Symbol

Fkbp8

Host or Source

E.coli

Protein Name

Peptidyl-prolyl cis-trans isomerase FKBP8

Gene Name URL

Fkbp8

Nucleotide Accession Number

NM_001111066.1

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