FKBP8 Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
FK506 binding protein 8
Gene Aliases
38 kDa FK506-binding protein;38 kDa FKBP;38kD;38kDa; FK506-binding protein 38; FK506-binding protein 8; Fkbp3; Fkbp38; FKBP-38; FKBP-8; FKBPR38; mFKBP38; peptidyl-prolyl cis-trans isomerase FKBP8; PPIase FKBP8; rotamase.
Gene ID
14232
Accession Number
NP_001104536.1
Reactivity
Mouse|Mus musculus
Target
Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis (By similarity) . Required for normal embryonic development.
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
26kDa
Protein Length
Recombinant
NCBI Gene Symbol
Fkbp8
Host or Source
E.coli
Protein Name
Peptidyl-prolyl cis-trans isomerase FKBP8
Gene Name URL
Fkbp8
Nucleotide Accession Number
NM_001111066.1
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