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IL36RN Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Interleukin 36 receptor antagonist

Gene Aliases

AI413231; FIL1d; Fil1delta; If36rn; IL1; IL-1; IL-1 delta; Il1f5; IL-1F5; IL1H; Il-1h3; Il1hy1; IL-1HY1; IL-1L1; IL-36Ra; interleukin 1 family, member 5 (delta) ; interleukin 1 receptor antagonist homolog 1; interleukin-1 delta; interleukin-1 family member 5; interleukin-1 homolog 3; interleukin-1 HY1; interleukin-1-like protein 1; interleukin-36 receptor antagonist protein.

Gene ID

54450

Accession Number

NP_001139559.1

Reactivity

Mouse|Mus musculus

Target

Inhibits the activity of interleukin-36 (IL36A, IL36B and IL36G) by binding to receptor IL1RL2/IL-36R and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

20.83kDa

Protein Length

Recombinant

NCBI Gene Symbol

Il36rn

Host or Source

E.coli

Protein Name

Interleukin-36 receptor antagonist protein

Gene Name URL

Il36rn

Nucleotide Accession Number

NM_001146087.1

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