IL36RN Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Interleukin 36 receptor antagonist
Gene Aliases
AI413231; FIL1d; Fil1delta; If36rn; IL1; IL-1; IL-1 delta; Il1f5; IL-1F5; IL1H; Il-1h3; Il1hy1; IL-1HY1; IL-1L1; IL-36Ra; interleukin 1 family, member 5 (delta) ; interleukin 1 receptor antagonist homolog 1; interleukin-1 delta; interleukin-1 family member 5; interleukin-1 homolog 3; interleukin-1 HY1; interleukin-1-like protein 1; interleukin-36 receptor antagonist protein.
Gene ID
54450
Accession Number
NP_001139559.1
Reactivity
Mouse|Mus musculus
Target
Inhibits the activity of interleukin-36 (IL36A, IL36B and IL36G) by binding to receptor IL1RL2/IL-36R and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
20.83kDa
Protein Length
Recombinant
NCBI Gene Symbol
Il36rn
Host or Source
E.coli
Protein Name
Interleukin-36 receptor antagonist protein
Gene Name URL
Il36rn
Nucleotide Accession Number
NM_001146087.1
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