What is the catalog number for FGA Recombinant Protein?

The catalog number for FGA Recombinant Protein is OPCD03170-200UG.

What sizes are available for FGA Recombinant Protein?

FGA Recombinant Protein is available in the following size(s): 200 µg.

Is FGA Recombinant Protein in stock?

FGA Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

FGA Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Fibrinogen alpha chain

Gene Aliases

Fi; Fib; fibrinogen alpha chain; fibrinogen, A alpha polypeptide.

Gene ID

14161

Accession Number

NP_001104518.1

Reactivity

Mouse|Mus musculus

Target

Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots (PubMed:7649481) . In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization (PubMed:11389004) . Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood (PubMed:7649481) . However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo (PubMed:10930441) . Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway (PubMed:19332769) . Maternal fibrinogen is essential for successful pregnancy (PubMed:7649481) . Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage (PubMed:12629066) . May also facilitate the immune response via both innate and T-cell mediated pathways (PubMed:23487423) .

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol