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FBXL3 Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

F-box and leucine-rich repeat protein 3

Gene Aliases

AU041772; AW212966; FBK; Fbl; Fbl3a; F-box and leucine-rich repeat protein 3a; F-box/LRR-repeat protein 3; F-box/LRR-repeat protein 3A; Fbxl; Fbxl3a; Ov; Ovtm; Pla; Play68; protein after-hours; protein overtime.

Gene ID

50789

Accession Number

NP_056637.1

Reactivity

Mouse|Mus musculus

Target

Substrate-recognition component of the SCF (FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF (FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF (FBXL3) complex is counteracted by the SCF (FBXL21) complex.

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

37kDa

Protein Length

Recombinant

NCBI Gene Symbol

Fbxl3

Host or Source

E.coli

Protein Name

F-box/LRR-repeat protein 3

Gene Name URL

Fbxl3

Nucleotide Accession Number

NM_015822.2

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