DYRK1A Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Dual specificity tyrosine phosphorylation regulated kinase 1A
Gene Aliases
Dual specificity tyrosine- (Y) -phosphorylation regulated kinase 1A; dual specificity tyrosine-phosphorylation-regulated kinase 1A; dual specificity YAK1-related kinase; DYRK; DYRK1; HP86; MNB; mnb protein kinase homolog hp86; MNB/DYRK protein kinase; MNBH; MRD7; protein kinase minibrain homolog; serine/threonine kinase MNB; serine/threonine-specific protein kinase.
Gene ID
1859
Accession Number
NP_001387.2
Reactivity
Homo sapiens|Human
Target
Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6 (By similarity) . Exhibits a substrate preference for proline at position P+1 and arginine at position P-3. Has pro-survival function and negatively regulates the apoptotic process. Promotes cell survival upon genotoxic stress through phosphorylation of SIRT1. This in turn inhibits TP53 activity and apoptosis (By similarity) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
37kDa
Protein Length
Recombinant
NCBI Gene Symbol
DYRK1A
Host or Source
E.coli
Protein Name
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Gene Name URL
DYRK1A
Nucleotide Accession Number
NM_001396.3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
