CYR61 Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Cellular communication network factor 1
Gene Aliases
3CH61; AI325051; CCN; CCN family member 1; Cyr6; Cyr61; cysteine rich protein 61; cysteine-rich angiogenic inducer 61; IBP-10; IGF-binding protein 10; Igfbp10; IGFBP-10; insulin-like growth factor-binding protein 10; intermediate early; protein CYR61.
Gene ID
16007
Accession Number
NP_034646.1
Reactivity
Mouse|Mus musculus
Target
Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5 (By similarity) . CYR61-mediated gene regulation is dependent on heparin-binding (By similarity) . Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1 (By similarity) . Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-1/beta-5 and cell proliferation through integrin alpha-v/beta-3 (By similarity) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
28kDa
Protein Length
Recombinant
NCBI Gene Symbol
Ccn1
Host or Source
E.coli
Protein Name
Protein CYR61
Gene Name URL
Ccn1
Nucleotide Accession Number
NM_010516.2
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