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CYP27B1 Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Cytochrome P450 family 27 subfamily B member 1

Gene Aliases

1alpha (OH) ase;25 hydroxyvitamin D3-1-alpha hydroxylase;25-hydroxyvitamin D (3) 1-alpha-hydroxylase;25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial;25-OHD-1 alpha-hydroxylase; calcidiol 1-monooxygenase; CP2B; CYP1; CYP1alpha; CYP27B; cytochrome p450 27B1; cytochrome P450 subfamily XXVIIB polypeptide 1; cytochrome P450, family 27, subfamily B, polypeptide 1; cytochrome P450C1 alpha; cytochrome P450VD1-alpha; P450c1; PDDR; VD3 1A hydroxylase; VDD1; VDDR; VDDRI; VDR.

Gene ID

1594

Accession Number

NP_000776.1

Reactivity

Homo sapiens|Human

Target

Catalyzes the conversion of 25-hydroxyvitamin D3 (25 (OH) D3) to 1-alpha,25-dihydroxyvitamin D3 (1alpha,25 (OH) (2) D3), and of 24,25-dihydroxyvitamin D3 (24,25 (OH) (2) D3) to 1-alpha,24,25-trihydroxyvitamin D3 (1alpha,24,25 (OH) (3) D3) . Is also active with 25-hydroxy-24-oxo-vitamin D3. Plays an important role in normal bone growth, calcium metabolism, and tissue differentiation.

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

31.79kDa

Protein Length

Recombinant

NCBI Gene Symbol

CYP27B1

Host or Source

E.coli

Protein Name

25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial

Gene Name URL

CYP27B1

Nucleotide Accession Number

NM_000785.3

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