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CYP24A1 Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Cytochrome P450 family 24 subfamily A member 1

Gene Aliases

1,25-@dihydroxyvitamin D3 24-hydroxylase;1,25-dihydroxyvitamin D (3) 24-hydroxylase, mitochondrial;24-OHase; CP24; CYP24; cytochrome P450 24A1; cytochrome P450, family 24, subfamily A, polypeptide 1; cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase) ; cytochrome P450-CC24; exo-mitochondrial protein; HCAI; HCINF1; P450-CC24; vitamin D 24-hydroxylase; vitamin D (3) 24-hydroxylase.

Gene ID

1591

Accession Number

NP_000773.2

Reactivity

Homo sapiens|Human

Target

Has a role in maintaining calcium homeostasis. Catalyzes the adrenodoxin-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D (3) ) and calcitriol (1-alpha,25-dihydroxyvitamin D (3) ) . The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D (3) -26,23-lactone as end product.

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

28kDa

Protein Length

Recombinant

NCBI Gene Symbol

CYP24A1

Host or Source

E.coli

Protein Name

1,25-dihydroxyvitamin D (3) 24-hydroxylase, mitochondrial

Gene Name URL

CYP24A1

Nucleotide Accession Number

NM_000782.4

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