CYP24A1 Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Cytochrome P450 family 24 subfamily A member 1
Gene Aliases
1,25-@dihydroxyvitamin D3 24-hydroxylase;1,25-dihydroxyvitamin D (3) 24-hydroxylase, mitochondrial;24-OHase; CP24; CYP24; cytochrome P450 24A1; cytochrome P450, family 24, subfamily A, polypeptide 1; cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase) ; cytochrome P450-CC24; exo-mitochondrial protein; HCAI; HCINF1; P450-CC24; vitamin D 24-hydroxylase; vitamin D (3) 24-hydroxylase.
Gene ID
1591
Accession Number
NP_000773.2
Reactivity
Homo sapiens|Human
Target
Has a role in maintaining calcium homeostasis. Catalyzes the adrenodoxin-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D (3) ) and calcitriol (1-alpha,25-dihydroxyvitamin D (3) ) . The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D (3) -26,23-lactone as end product.
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
28kDa
Protein Length
Recombinant
NCBI Gene Symbol
CYP24A1
Host or Source
E.coli
Protein Name
1,25-dihydroxyvitamin D (3) 24-hydroxylase, mitochondrial
Gene Name URL
CYP24A1
Nucleotide Accession Number
NM_000782.4
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