E3 ligase Ligand 35

E3 ligase Ligand 35 serves as the E3 ligase ligand for PROTAC SMARCA2 degrader-27 (HY-168229)[1].

Ligands for E3 Ligase

Reference compound

PROTAC

Cancer-programmed cell death

Cancer

https://www.medchemexpress.com/e3-ligase-ligand-35.html

OC1=NOC([C@H](C(N2C[C@H](O)C[C@H]2C(N[C@H](C3=CC(F)=C(C#N)C=C3)C)=O)=O)C(C)C)=C1

444.46

[1]Michael Berlin, et al. Brm targeting compounds and associated methods of use. Patents, WO2023097031, 2023-06-01.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-168232/E3-ligase-Ligand-35-DataSheet-MedChemExpress.pdf

http://file.medchemexpress.com/batch_PDF/HY-168232/

No Development Reported