E3 ligase Ligand 35
E3 ligase Ligand 35 serves as the E3 ligase ligand for PROTAC SMARCA2 degrader-27 (HY-168229) [1].
Product Specifications
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-35.html
Smiles
OC1=NOC([C@H](C(N2C[C@H](O)C[C@H]2C(N[C@H](C3=CC(F)=C(C#N)C=C3)C)=O)=O)C(C)C)=C1
Molecular Formula
C22H25FN4O5
Molecular Weight
444.46
References & Citations
[1]Michael Berlin, et al. Brm targeting compounds and associated methods of use. Patents, WO2023097031, 2023-06-01.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168232/E3-ligase-Ligand-35-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168232/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
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