What is the catalog number for PPP3CA Recombinant Protein?

The catalog number for PPP3CA Recombinant Protein is OPCD01848-50UG.

What sizes are available for PPP3CA Recombinant Protein?

PPP3CA Recombinant Protein is available in the following size(s): 50 µg.

Is PPP3CA Recombinant Protein in stock?

PPP3CA Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

PPP3CA Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Protein phosphatase 3 catalytic subunit alpha

Gene Aliases

ACCIID; calcineurin A alpha; Calmodulin-dependent calcineurin A subunit alpha isoform; CALN; CALNA; CALNA1; CAM-PRP catalytic subunit; CCN1; CNA1; DEE91; IECEE; IECEE1; PPP2B; protein phosphatase 3 catalytic subunit alpha isozyme; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform.

Gene ID

5530

Accession Number

NP_000935.1

Reactivity

Homo sapiens|Human

Target

Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca (2+) -mediated signals (PubMed:15671020, PubMed:18838687, PubMed:19154138, PubMed:23468591) . Many of the substrates contain a PxIxIT motif and/or a LxVP motif (PubMed:17498738, PubMed:17502104, PubMed:23468591, PubMed:27974827, PubMed:22343722) . In response to increased Ca (2+) levels, dephosphorylates and activates phosphatase SSH1 which results in cofilin dephosphorylation (PubMed:15671020) . In response to increased Ca (2+) levels following mitochondrial depolarization, dephosphorylates DNM1L inducing DNM1L translocation to the mitochondrion (PubMed:18838687) . Dephosphorylates heat shock protein HSPB1 (By similarity) . Dephosphorylates and activates transcription factor NFATC1 (PubMed:19154138) . In response to increased Ca (2+) levels, regulates NFAT-mediated transcription probably by dephosphorylating NFAT and promoting its nuclear translocation (PubMed:26248042) . Dephosphorylates and inactivates transcription factor ELK1 (PubMed:19154138) . Dephosphorylates DARPP32 (PubMed:19154138) .

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

39kDa

Protein Length

Recombinant

NCBI Gene Symbol

PPP3CA

Host or Source

E.coli

Protein Name

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

Gene Name URL

PPP3CA

Nucleotide Accession Number

NM_000944.4

Frequently Asked Questions

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