What is the catalog number for PPP3CA Recombinant Protein?

The catalog number for PPP3CA Recombinant Protein is OPCD01848-10UG.

What sizes are available for PPP3CA Recombinant Protein?

PPP3CA Recombinant Protein is available in the following size(s): 10 µg.

Is PPP3CA Recombinant Protein in stock?

PPP3CA Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

PPP3CA Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Protein phosphatase 3 catalytic subunit alpha

Gene Aliases

ACCIID; calcineurin A alpha; Calmodulin-dependent calcineurin A subunit alpha isoform; CALN; CALNA; CALNA1; CAM-PRP catalytic subunit; CCN1; CNA1; DEE91; IECEE; IECEE1; PPP2B; protein phosphatase 3 catalytic subunit alpha isozyme; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform.

Gene ID

5530

Accession Number

NP_000935.1

Reactivity

Homo sapiens|Human

Target

Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca (2+) -mediated signals (PubMed:15671020, PubMed:18838687, PubMed:19154138, PubMed:23468591) . Many of the substrates contain a PxIxIT motif and/or a LxVP motif (PubMed:17498738, PubMed:17502104, PubMed:23468591, PubMed:27974827, PubMed:22343722) . In response to increased Ca (2+) levels, dephosphorylates and activates phosphatase SSH1 which results in cofilin dephosphorylation (PubMed:15671020) . In response to increased Ca (2+) levels following mitochondrial depolarization, dephosphorylates DNM1L inducing DNM1L translocation to the mitochondrion (PubMed:18838687) . Dephosphorylates heat shock protein HSPB1 (By similarity) . Dephosphorylates and activates transcription factor NFATC1 (PubMed:19154138) . In response to increased Ca (2+) levels, regulates NFAT-mediated transcription probably by dephosphorylating NFAT and promoting its nuclear translocation (PubMed:26248042) . Dephosphorylates and inactivates transcription factor ELK1 (PubMed:19154138) . Dephosphorylates DARPP32 (PubMed:19154138) .

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol