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C2CD3 Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

C2 calcium-dependent domain containing 3

Gene Aliases

AU020772; C2 domain-containing protein 3; protein hearty.

Gene ID

277939

Accession Number

NP_001017985.2

Reactivity

Mouse|Mus musculus

Target

Component of the centrioles that acts as a positive regulator of centriole elongation (PubMed:24997988) . Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation (PubMed:24469809) . Required for primary cilium formation. Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3 (PubMed:19004860) .

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

36kDa

Protein Length

Recombinant

NCBI Gene Symbol

C2cd3

Host or Source

E.coli

Protein Name

C2 domain-containing protein 3

Gene Name URL

C2cd3

Nucleotide Accession Number

NM_001017985.2

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