RNF112 Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Ring finger protein 112
Gene Aliases
BFP; brain finger protein; neurolastin; RING finger protein 112; zinc finger protein 179; ZNF179.
Gene ID
7732
Accession Number
NP_009079.2
Reactivity
Homo sapiens|Human
Target
E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development. During embryonic development initiates neuronal differentiation by inducing cell cycle arrest at the G0/G1 phase through up-regulation of cell-cycle regulatory proteins (PubMed:28684796) . Plays a role not only in the fetal period during the development of the nervous system, but also in the adult brain, where it is involved in the maintenance of neural functions and protection of the nervous tissue cells from oxidative stress-induced damage. Exhibits GTPase and E3 ubiquitin-protein ligase activities. Regulates dendritic spine density and synaptic neurotransmission; its ability to hydrolyze GTP is involved in the maintenance of dendritic spine density (By similarity) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
31.28kDa
Protein Length
Recombinant
NCBI Gene Symbol
RNF112
Host or Source
E.coli
Protein Name
RING finger protein 112
Gene Name URL
RNF112
Nucleotide Accession Number
NM_007148.4
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
FY-AB41091-01 1 mL
FITC-Linked Anti-Histidine Rich Glycoprotein (HRG)
Sign In for Pricing
View Details FY-AB41091-02 100 µL
FITC-Linked Anti-Histidine Rich Glycoprotein (HRG)
Sign In for Pricing
View Details FY-AB41091-03 200 µL
FITC-Linked Anti-Histidine Rich Glycoprotein (HRG)
Sign In for Pricing
View Details