AIMP1 Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Aminoacyl tRNA synthetase complex interacting multifunctional protein 1
Gene Aliases
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1; ARS-interacting multifunctional protein 1; EMAP2; EMAPII; endothelial monocyte-activating polypeptide 2; endothelial-monocyte activating polypeptide II; HLD3; multisynthase complex auxiliary component p43; multisynthetase complex auxiliary component p43; p43; SCYE1; small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) .
Gene ID
9255
Accession Number
NP_001135887.1
Reactivity
Homo sapiens|Human
Target
Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase (PubMed:10358004) . Binds tRNA. Possesses inflammatory cytokine activity (PubMed:11306575) . Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation (By similarity) . Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels (By similarity) . Promotes dermal fibroblast proliferation and wound repair (PubMed:16472771) . Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum (By similarity) . Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations (PubMed:12237313) . Induces maturation of dendritic cells and monocyte cell adhesion (PubMed:11818442) . Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7 (PubMed:19362550) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
19kDa
Protein Length
Recombinant
NCBI Gene Symbol
AIMP1
Host or Source
E.coli
Protein Name
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1
Gene Name URL
AIMP1
Nucleotide Accession Number
NM_001142415.1
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