SYD5115
SYD5115 is an orally available TSH-R antagonist[1][2].
Product Specifications
UNSPSC
12352005
Target
TSH Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/syd5115.html
Purity
99.69
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O[C@H](C(C)(C)C)C)NC1=NC=C(N(C(C)=O)C2(C)C)C(C32CCC(F)(F)CC3)=N1
Molecular Formula
C22H32F2N4O3
Molecular Weight
438.51
References & Citations
[1]Karstens WFJ, et al. Discovery of SYD5115, a novel orally active small molecule TSH-R antagonist. Bioorg Med Chem. 2023 Apr 15;84:117258.|[2]Furmaniak J, et al. In vivo effects of a human thyroid-stimulating monoclonal autoantibody (M22) and a human thyroid-blocking autoantibody (K1-70) . Auto Immun Highlights. 2011 Sep 14;3 (1) :19-25.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC420325 20 µg
Zfp219 (ZNF219) (NM_001101672) Human Over-expression Lysate
Sign In for Pricing
View Details ![(3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone](https://cdn.genprice.uk/products/572/1874197135645/imageurl/trc-b671500-50mg.webp)
TRC-B671500-50MG 50 mg
(3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone
Sign In for Pricing
View Details 
