What is the catalog number for CPEB1 Recombinant Protein?

The catalog number for CPEB1 Recombinant Protein is OPCD00873-10UG.

What sizes are available for CPEB1 Recombinant Protein?

CPEB1 Recombinant Protein is available in the following size(s): 10 µg.

Is CPEB1 Recombinant Protein in stock?

CPEB1 Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

CPEB1 Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Cytoplasmic polyadenylation element binding protein 1

Gene Aliases

CPEB; CPEB-1; CPE-binding protein 1; CPE-BP1; cytoplasmic polyadenylation element-binding protein 1; h-CPEB; hCPEB-1.

Gene ID

64506

Accession Number

NP_001073001.1

Reactivity

Homo sapiens|Human

Target

Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism (PubMed:24990967) . In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity) . Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity) . Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity) . Induces the assembly of stress granules in the absence of stress. Required for cell cycle progression, specifically for prophase entry (PubMed:26398195) .

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol