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MFN1 Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Mitofusin 1

Gene Aliases

2310002F04Rik;6330416C07Rik; D3Ertd265; D3Ertd265e; HR; HR2; mitofusin-1; mKIAA4032; transmembrane GTPase MFN1.

Gene ID

67414

Accession Number

NP_077162.2

Reactivity

Mouse|Mus musculus

Target

Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:12527753, PubMed:23921378, PubMed:24513856, PubMed:15297672) . Membrane clustering requires GTPase activity (By similarity) . It may involve a major rearrangement of the coiled coil domains (PubMed:15297672) . Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:12527753) . Overexpression induces the formation of mitochondrial networks (in vitro) . Has low GTPase activity (By similarity) .

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

30kDa

Protein Length

Recombinant

NCBI Gene Symbol

Mfn1

Host or Source

E.coli

Protein Name

Mitofusin-1

Gene Name URL

Mfn1

Nucleotide Accession Number

NM_024200.4

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