UXT Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Ubiquitously expressed prefoldin like chaperone
Gene Aliases
Androgen receptor trapped clone 27 protein; ART-27; protein UXT; SKP2-associated alpha PFD 1; STAP1; ubiquitously expressed transcript protein.
Gene ID
8409
Accession Number
NP_004173.1
Reactivity
Homo sapiens|Human
Target
Involved in gene transcription regulation (PubMed:28106301, PubMed:21730289) . Acts in concert with the corepressor URI1 to regulate androgen receptor AR-mediated transcription (PubMed:11854421, PubMed:21730289) . Together with URI1, associates with chromatin to the NKX3-1 promoter region (PubMed:21730289) . Negatively regulates the transcriptional activity of the estrogen receptor ESR1 by inducing its translocation into the cytoplasm (PubMed:28106301) . May act as nuclear chaperone that facilitates the formation of the NF-kappa-B enhanceosome and thus positively regulates NF-kappa-B transcription activity (PubMed:17620405, PubMed:21307340) . Potential component of mitochondrial-associated LRPPRC, a multidomain organizer that potentially integrates mitochondria and the microtubular cytoskeleton with chromosome remodeling (PubMed:17554592) . Increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially through its association with LRPPRC (PubMed:17554592) . Suppresses cell transformation and it might mediate this function by interaction and inhibition of the biological activity of cell proliferation and survival stimulatory factors like MECOM (PubMed:17635584) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
21kDa
Protein Length
Recombinant
NCBI Gene Symbol
UXT
Host or Source
E.coli
Protein Name
Protein UXT
Gene Name URL
UXT
Nucleotide Accession Number
NM_004182.3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15373763 1 Vial
Lentiviral human ABCF3 sgRNA gene knockout kit - Lentiviral human ABCF3 sgRNA gene knockout kit (plasmid)
Ask
View Details 
GTR15352361 1 Vial
Lentiviral human MAGEE2 shRNA (UAS) - Lentiviral human MAGEE2 shRNA (UAS, iRFP) (25)
Ask
View Details GTR15278253 1 Vial
Lentiviral mouse Slf1 shRNA (UAS) - Lentiviral mouse Slf1 shRNA (UAS, GFP) (100)
Ask
View Details