CBY1 Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Chibby family member 1, beta catenin antagonist
Gene Aliases
Arb1; ARPP-binding protein; C22orf2; CBY; chibby CTNNB1-mediated transcription inhibitor; chibby homolog 1; Chibby1; coiled-coil protein PIGEA-14; cytosolic leucine-rich protein; HS508I15A; PGEA1; PIGEA14; PIGEA-14; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; polycystin-2 interactor, Golgi- and endoplasmic reticulum-associated protein, 14 kDa; protein chibby homolog 1.
Gene ID
25776
Accession Number
NP_001002880.2
Reactivity
Homo sapiens|Human
Target
Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
16kDa
Protein Length
Recombinant
NCBI Gene Symbol
CBY1
Host or Source
E.coli
Protein Name
Protein chibby homolog 1
Gene Name URL
CBY1
Nucleotide Accession Number
NM_001002880.1
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