PDIA6 Recombinant Protein
Product Specifications
Gene Name
Protein disulfide isomerase family A member 6
Gene Aliases
Endoplasmic reticulum protein 5; epididymis secretory sperm binding protein; ER protein 5; ERP5; P5; protein disulfide isomerase P5; protein disulfide isomerase-associated 6; protein disulfide isomerase-related protein; protein disulfide-isomerase A6; thioredoxin domain containing 7 (protein disulfide isomerase) ; thioredoxin domain-containing protein 7; TXNDC7.
Gene ID
10130
Accession Number
NP_001269633.1
Reactivity
Homo sapiens|Human
Target
May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:12204115) . Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (PubMed:24508390) . May also regulate the UPR via the EIF2AK3 UPR sensor (PubMed:24508390) . Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (PubMed:15466936) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
50kDa
Protein Length
Recombinant
NCBI Gene Symbol
PDIA6
Host or Source
E.coli
Protein Name
Protein disulfide-isomerase A6
Gene Name URL
PDIA6
CAS Number
9000-83-3
Nucleotide Accession Number
NM_001282704.1
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