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HCFC1 Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

Host cell factor C1

Gene Aliases

AW060991; C1 factor; HCF; HCF1; host cell factor 1; VP16 accessory protein.

Gene ID

15161

Accession Number

NP_032250.2

Reactivity

Mouse|Mus musculus

Target

Involved in control of the cell cycle (PubMed:9334261, PubMed:9990006) . Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15 (INK4b) promoter and inhibits its ability to recruit p300 (By similarity) . Coactivator for EGR2 and GABP2 (By similarity) . Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription respectively) together (By similarity) . As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (By similarity) . Recruits KMT2E to E2F1 responsive promoters promoting transcriptional activation and thereby facilitates G1 to S phase transition (By similarity) .

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

29kDa

Protein Length

Recombinant

NCBI Gene Symbol

Hcfc1

Host or Source

E.coli

Protein Name

Host cell factor 1

Gene Name URL

Hcfc1

Nucleotide Accession Number

NM_008224.4

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