7-Methylxanthine

7-Methylxanthine is an orally active methyl derivative of xanthine and a non-selective adenosine receptor antagonist. 7-Methylxanthine is also one of the purine components of human urinary calculi. 7-Methylxanthine has anti-myopia activity[1][2].

Product Specifications

CAS Number

[552-62-5]

UNSPSC

12352005

Hazard Statement

H302

Target

Adenosine Receptor; Endogenous Metabolite

Type

Natural Products

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/7-Methyl-1H-purine-2,6_3H,7H_-dione.html

Purity

99.94

Solubility

DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CN1C=NC2=C1C(=O)NC(=O)N2

Molecular Formula

C6H6N4O2

Molecular Weight

166.14

Precautions

H302

References & Citations

[1]Caubet MS, et al. Determination of urinary 13C-caffeine metabolites by liquid chromatography-mass spectrometry: the use of metabolic ratios to assess CYP1A2 activity. J Pharm Biomed Anal. 2004 Feb 4;34 (2) :379-89.|[2]Hung LF, et al. The Adenosine Receptor Antagonist, 7-Methylxanthine, Alters Emmetropizing Responses in Infant Macaques. Invest Ophthalmol Vis Sci. 2018 Jan 1;59 (1) :472-486.