ABCG8 Recombinant Protein
Product Specifications
Gene Name
ATP binding cassette subfamily G member 8
Gene Aliases
1300003C16Rik; AI114946; ATP-binding cassette sub-family G member 8; ATP-binding cassette, sub-family G (WHITE), member 8; Ster; sterolin 2; sterolin-2.
Gene ID
67470
Accession Number
NP_001272934.1
Reactivity
Mouse|Mus musculus
Target
ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg (2+) - and ATP-dependent sterol transport across the cell membrane (PubMed:16352607, PubMed:16867993, PubMed:18402465) . Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:12444248, PubMed:14504269, PubMed:14657202, PubMed:25378657) . Plays an important role in preventing the accumulation of dietary plant sterols in the body (PubMed:12444248, PubMed:14657202) . Required for normal sterol homeostasis (PubMed:12444248, PubMed:14657202) . The heterodimer with ABCG5 has ATPase activity (PubMed:16352607, PubMed:16867993) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
34kDa
Protein Length
Recombinant
NCBI Gene Symbol
Abcg8
Host or Source
E.coli
Protein Name
ATP-binding cassette sub-family G member 8
Gene Name URL
Abcg8
CAS Number
9000-83-3
Nucleotide Accession Number
NM_001286005.1
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