What is the catalog number for TAP2 Recombinant Protein?

The catalog number for TAP2 Recombinant Protein is OPCD00376-50UG.

What sizes are available for TAP2 Recombinant Protein?

TAP2 Recombinant Protein is available in the following size(s): 50 µg.

Is TAP2 Recombinant Protein in stock?

TAP2 Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

TAP2 Recombinant Protein

Selected Variant

OPCD00376-50UG

Size: 50 µg

Product Specifications

CAS Number

9000-83-3

Gene Name

Transporter 2, ATP binding cassette subfamily B member

Gene Aliases

ABC transporter, MHC 2; ABC18; ABCB3; antigen peptide transporter 2; APT2; ATP-binding cassette sub-family B member 3; ATP-binding cassette, sub-family B (MDR/TAP), member 3; D6S217E; peptide supply factor 2; peptide transporter involved in antigen processing 2; peptide transporter PSF2; Peptide transporter TAP2; PSF2; PSF-2; really interesting new gene 11 protein; RING11; transporter 2, ABC (ATP binding cassette) ; transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) .

Gene ID

6891

Accession Number

NP_000535.3

Reactivity

Homo sapiens|Human

Target

Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. Inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. Inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP1 and prevents the conformational rearrangement of TAP induced by peptide binding. Inhibited by human adenovirus E3-19K glycoprotein, which binds the TAP complex and acts as a tapasin inhibitor, preventing MHC class I/TAP association.

Conjugation

Unconjugated

Type

Protein

Source

E.coli

Applications

Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

200 ug/mL (prior to lyoph)

Format

Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Reconstitution

2°C to 8°C|-80°C

Molecular Weight

28kDa

Protein Length

Recombinant

NCBI Gene Symbol

TAP2

Host or Source

E.coli

Protein Name

Antigen peptide transporter 2

Gene Name URL

TAP2

Nucleotide Accession Number

NM_000544.3

Price

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

CD73 (Immuno-Oncology Target) (NT5E/2505), CF405S conjugate, 0.1mg/mL

BNC042505-500 1x 500 µL