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CCL3 Protein

Product Specifications

Gene Name

Chemokine (C-C motif) ligand 3

Gene Aliases

MIP1A, SCYA3, G0S19-1, LD78ALPHA, MIP-1-alpha

Gene ID

6348

Target

Macrophage inflammatory proteins 1-alpha (MIP1alpha) (CCL3) binds to cell surface receptors CCR1 and CCR5. It is proinflammatory, leading to chemotaxis and activation of immune cells. It also inhibits proliferation of hematopoietic stem cells. Moreover, by binding to one of the HIV coreceptors, CCR5, it suppresses HIV infection.

Type

Protein

Source

E. coli

Applications

CA

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Bioactivity

EC50 = 0.2 nM determined by Migration Assay in cells expressing recombinant CCR5

Format

Lyophilized

Reconstitution

Shipping: //Room Temp

Molecular Weight

7.716 kDa

NCBI Gene Symbol

CCL3

Gene Name URL

CCL3

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