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UGT1A4 Recombinant Protein (Human)

Product Specifications

CAS Number

9000-83-3

Gene Name

UDP glucuronosyltransferase family 1 member A4

Gene Aliases

Bilirubin UDP-glucuronosyltransferase isozyme 2; Bilirubin-specific UDPGT isozyme 1; bilirubin-specific UDPGT isozyme 2; GNT1; hUG-BR1; HUG-BR2; UDP glucuronosyltransferase 1 family, polypeptide A4; UDP glycosyltransferase 1 family, polypeptide A4; UDP-glucuronosyltransferase 1 family polypeptide A4s; UDP-glucuronosyltransferase 1-1; UDP-glucuronosyltransferase 1-4; UDP-glucuronosyltransferase 1-A; UDP-glucuronosyltransferase 1A1; UDP-glucuronosyltransferase 1A4; UDP-glucuronosyltransferase 1-D; UDPGT; UDPGT 1-1; UDPGT 1-4; UGT1; UGT1.1; UGT1.4; UGT1-01; UGT1-04; UGT1A; UGT-1A; UGT1A1; UGT1A4S; UGT1D; UGT-1D.

Gene ID

54657

Accession Number

NP_009051

Reactivity

Homo sapiens|Human

Target

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1 (By similarity) .

Type

Protein

Source

E.coli

Sequence

GKVLVVPTDGSPWLSMREALRELHARGHQAVVLTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNVSLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDLDFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQREVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid or Lyophilized powder

Buffer

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution

-20°C or -80°C

Molecular Weight

61 kDa

Protein Length

Recombinant

NCBI Gene Symbol

UGT1A4

Protein Name

UDP-glucuronosyltransferase 1-4

Gene Name URL

UGT1A4

Nucleotide Accession Number

NM_007120

Frequently Asked Questions

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