IFNAR2 Recombinant Protein (Human)
Product Specifications
CAS Number
9000-83-3
Gene Name
Interferon alpha and beta receptor subunit 2
Gene Aliases
Human interferon alpha/beta receptor; IFNABR; IFN-alpha/beta receptor 2; IFNalpha/beta receptor subunit 2; IFN-alpha-REC; IFNARB; IFN-R; IFN-R-2; IMD45; interferon (alpha, beta and omega) receptor 2; interferon alpha binding protein; interferon alpha/beta receptor 2; interferon receptor; interferon-alpha/beta receptor beta chain; type I interferon receptor 2.
Gene ID
3455
Accession Number
NP_000865
Reactivity
Homo sapiens|Human
Target
Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation (PubMed:26424569) . Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1 (PubMed:8181059, PubMed:7665574, PubMed:7759950) . Isoform 3 is a potent inhibitor of type I IFN receptor activity (PubMed:7759950) .
Type
Protein
Source
E.coli
Sequence
ISYDSPDYTDESCTFKISLRNFRSILSWELKNHSIVPTHYTLLYTIMSKPEDLKVVKNCANTTRSFCDLTDEWRSTHEAYVTVLEGFSGNTTLFSCSHNFWLAIDMSFEPPEFEIVGFTNHINVMVKFPSIVEEELQFDLSLVIEEQSEGIVKKHKPEIKGNMSGNFTYIIDKLIPNTNYCVSVYLEHSDEQAVIKSPLKCTLLPPGQESESAESAK
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
-20°C or -80°C
Molecular Weight
40.8 kDa
Protein Length
Recombinant
NCBI Gene Symbol
IFNAR2
Protein Name
Interferon alpha/beta receptor 2
Gene Name URL
IFNAR2
Nucleotide Accession Number
NM_000874
Frequently Asked Questions
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